Fig. 10. Shroom1 expression is sufficient to elicit apical accumulation of -tubulin in naïve epithelial cells. (A) Surface view of blastomeres stained for -tubulin. Shroom1-expressing cells (right) accumulate high levels of -tubulin at cell-cell junctions. (B) Section view of blastomeres stained for -tubulin. (b') Shroom1-expressing cells [indicated by anti-Myc staining (red)] accumulate excess -tubulin at cell-cell boundaries. (C) Model for Shroom3-mediated cell shape changes in neural epithelial cells. Model is based on data from the current work and also on the work of Hildebrand (Hildebrand, 2005) and Haigo et al. (Haigo et al., 2003).