Development -- Lee et al. 134 (7): 1431 Figure IG7

(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.

Fig. 7. Expression of Shroom3 in epidermal cells recapitulates the events underlying neuroepithelial cell shape change. (A) Control epidermis stained for ${alpha}$ -tubulin. (B) Epidermis expressing Shroom3 stained for ${alpha}$ -tubulin. Cells expressing Shroom3 (marked by anti-Myc; b') constrict and elongate. Parallel arrays of MTs emanate from the apical cell surface. (C) Control epidermis stained for ${gamma}$ -tubulin. (D) Epidermis expressing Shroom3 stained for ${gamma}$ -tubulin. Cells expressing Shroom3 in this panel (marked by anti-Myc, red; d') are only slightly constricted, but are elongated and contain a broad, diffuse accumulation of ${gamma}$ -tubulin. (E) A single epidermis cell expressing high levels of Shroom3 apically constricts and also elongates. (e') Anti- ${alpha}$ -tubulin staining of the cell shown in E.