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Figure 1


Fig. 1. Effect of N-Myc deficiency on mouse limb bud formation. (A) Comparison of PC control embryos with PC-NMycf/f and N-Myc null embryos at E10.5. Arrows indicate forelimb and hindlimb buds. Note that N-Myc null embryos die between E10.5 and 11.5. (B) Representative whole-mount in situ hybridization results showing forelimb expression of the indicated genes at E10.5. At least three sets of embryos were used for each probe. A, anterior; P, posterior.