Fig. 6. Defects in cell morphology and organ formation during embryogenesis. (A-D) Differential-interference contrast images of cleared embryos of wild-type (Ler) (A), ale1-2 (B), ale2-1 (C) and ale1-2 ale2-1 double-mutant (D) embryos. Embryos are shown at the globular (G), the triangular (Tr), the heart (H) and the torpedo (T) stages. The three insets show gross morphology of respective embryos. (E) Frequencies of embryos with slightly swollen surfaces (white bars) and nearly spherical protodermal cells (black bars). The abnormal embryos from the indicated parents were scored. Scale bars: 20 µm.