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Figure 2


Fig. 2. Expression of the Tgfb3 and Irf6 genes is unaffected in Snai2-/- and Snai1+/- Snai2-/- palates at E14.5. (A-C) In situ hybridization showing expression of Tgfb3 along the MES of control embryos and clear expression at the adjacent but unfused MEE of mutant embryos. (D-F) The Irf6 gene is expressed throughout the oral and nasal epithelia in both control and mutant embryos. ps, palatal shelf. Scale bar: 200 µm.