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Figure 7


Fig. 7. Motoneurons are generated normally in Hoxc10-/-/Hoxd10-/- double-mutant embryos. Cross-sections of lumbar spinal cord of control and double-mutant embryos stained for (A) Olig2, a marker for motoneuron progenitors, and (B) Isl1 to label newly generated postmitotic motoneurons. There were no apparent differences in the numbers of Olig2+ motoneuron progenitors or Isl1+ motoneurons between control and double-mutant embryos. D, dorsal root ganglion; M, motoneurons. Scale bars: 100 µm.