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Figure 3


Fig. 3. Notch, but not Sox3, attenuates expression of Ngn2 and E47. (A,B) Expression of NICD for 42 hours attenuated Ngn2 (A) and E47 expression (B). (C,D) Transfection of dnCSL for 10-20 hours increased Ngn2 (C) and E47 expression (D). (E,F) Misexpression of Sox3 for 42 hours did not alter the levels of Ngn2 (E) or E47 expression. Black and white representations of A-F are shown in Fig. S4 (see supplementary material). Scale bar: 40 µm.