Fig. 4. Phenotype of 7-week-old Catnb^lox(e3)/+; AMH-Cre^tg/+ males. (A) Catnb^lox(e3)/+; AMH-Cre^tg/+ males developed severely reduced size of testes and had retained uterus (b, light microscopy; c, Hematoxylin and Eosin staining). ep, epididymis; sv, seminal vesicle; t, testis; u, uterus; vd, vas deferens. (B) Testis sections stained with Hematoxylin and Eosin, and anti-3β-HSD antibody showing normal tubular architecture in control testes (a-c) and disruption of tubules in mutant testes (d-f). Scale bars in B: 60 µm in a,d; 20 µm in b,c,e,f.