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Figure 6


Fig. 6. Turnover of Phox2b-expressing cells. Pancreas from Nkx2.2+/+ (A,B) and Nkx2.2-/- (C-F) mouse embryos at E12.5 (A), E13.5 (B,C), and E15.5 (D-F) were co-stained by immunofluorescence for Pdx1 (FITC, green) and the apoptosis marker cleaved caspase-3 (Cy3, red; A-C), or for Phox2b (Cy3, red; D,F) and the replication marker Ki67 (FITC, green; E,F). Scale bars: 50 µm.