Fig. 4. Gene expression at E3-4 in BA1 mesenchyme after graft of QT6-Shh
cells. (A-D) Expression patterns of Noggin (A),
Pitx1 (B), Gli3 (C) and dHand (D) in BA1 mesenchyme
at E3 and E4. On the grafted side (left) Noggin, Pitx1 and
dHand expression is extended in a mediocaudal direction (arrows). (C)
Gli3 is downregulated in the region corresponding to dHand
expression (arrow).