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Figure 1


Fig. 1. Expression of TAG-1 and L1 on spinal sensory afferents. (A-H) Transverse sections of E12.5 spinal cord immunolabelled for TrkA and L1 (A-D) or L1 and TAG-1 (E-H). Magnified images of the dorsal funiculus (DF) from C and G shown in D and H, respectively. Asterisks indicate L1+, TAG-1/TrkA- region. (I-P) Transverse sections of E15.5 spinal cord with TrkA and L1 (I-L) or TAG-1 and L1 (M-P). Higher magnification of the DF from K and O is shown in L and P. Asterisks indicate L1+, TAG-1/TrkA- region. Arrows indicate position of TrkA- proprioceptive fibres emanating from the L1+, TAG-1/TrkA- region. Arrowheads indicate TrkA+ fibres. Scale bar: ~100 µm.