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Figure 1


Fig. 1. Alignment of the predicted amino acid sequence of LvNumb and Human Numb1 proteins. (A) Identical residues are denoted by an asterisk and conserved by `.' or `:'. The four conserved domains are labeled. (B) A molecular phylogeny of the Numb and Numb-like family members. Abbreviations: Ce, C. elegans; Mm, mouse; Rn, rat; Hs, human; Tn, Tetraodon (puffer fish); Dr, zebrafish; Xt, Xenopus tropocalis; Gg, chicken; Ci, Ciona; Lv, Lytechinus; Dm, Drosophila.