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Figure 5


Fig. 5. Proliferation and development of non-hematopoietic tissues, including the vascular system, are normal in c-Myc-deficient embryos. (A) Immunohistochemical analysis of BrdU incorporation in control (left) and c-Myc-deficient (right) embryos at E11.0. (B) PECAM (CD31) staining in wholemounts (top) and histological sections (bottom) show normal development of the vascular system in the embryo, the placenta and the YS of Sox2Cre;c-mycflox/flox embryos at E11.0.