Fig. 6. Hematopoietic- and endothelial-specific elimination of c-Myc via
Tie2Cre. (A) Phenotypes of control and
Tie2Cre;c-mycflox/flox
embryos and YS at E11.0. (B) Quantitative analysis of total
CD45+ cells per E11.0 embryos (**P
0.001).
(C) FACS analysis showing the expression of the stem cell markers Kit
(CD117) and AA4.1 (CD93) in CD45+ hematopoietic cells of control
(left) and
Tie2Cre;c-mycflox/flox
(right) embryos at E11.0. Numbers represent percentages in the
CD45+ population.