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Figure 1


Fig. 1. Mouse Cdx gene overexpresser (OE) constructs for preparation of transgenic mice. The OE constructs (A-C) were derived as modifications of Cdx/lacZ reporter constructs (D-F) previously found to mimic expression of endogenous Cdx genes in early embryos (Gaunt et al., 2003; Gaunt et al., 2005). (G-I) Cdx1, Cdx2 and Cdx4 genomic maps. Grey boxes indicate Cdx exons; hatched boxes indicate lacZ/SV40polyA DNA; K, KpnI; H, HindIII; R, EcoRI; Sp, SpeI; Bg, BglII; S, SalI.