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Figure 8


Fig. 8. Cdx OE embryos show forward shifts in Hoxa7/lacZ expression without, necessarily, earlier activation. (A-D) At 10.5 days, the anterior boundaries in prevertebrae (v), lateral plate mesoderm (lpm) and spinal ganglia (sg) of wild-type (A) and OE (B-D) embryos are shown. The OE2 embryo possesses a club-tail. (E) At 8 to 8.25 days, OE1 and OE4 embryos commence Hox/lacZ activity in the primitive streak region (white arrows) at apparently the same developmental stage (headfold) as wild-type (non OE) embryos.