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Figure 3


Fig. 3. picasso is allelic to erbb3b. (A) Schematic of erbb3b cDNA showing picasso lesions. RL, receptor L (ligand-binding) domains; C, furin-like cysteine-rich domains; PK, protein kinase domain; TM, transmembrane domain; arrow, N835 interruption to kinase domain characteristic of erbb3. (B) Premature stop codon in pcswp.r2e2 (C433T: Q145stop). (C) Premature stop codon (arrow) in pcsut.r4e1 (T2043A: Y681stop), as shown versus wild type.