Fig. 1. spon-1 mutants are defective in epidermal morphogenesis and
muscle attachment. (A) The wild-type L1 larva has a smooth
epidermal shape. (B,C) spon-1(e2623) L1 larvae and
adults display variable defects in epidermal morphology. The bent body
phenotype is more obvious during early larval stages (B), whereas some adults
display `pinched' head morphology (arrow, C); other e2623 phenotypes
include egg laying defects and a slightly shorter body length. (D) A
wild-type embryo at 3-fold stage. (E) spon-1(ju402) mutant
embryo, displaying elongation arrest and uneven epidermal morphology (arrow).
(F) spon-1(ju430) mutant hatchling showing elongation arrest
with lumpy 2-fold morphology and detached body wall muscles (arrow). Scale
bar: 10 µm.