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Figure 7


Fig. 7. Proposed cellular mechanism for the control of small intestinal fibroblast differentiation by Fgf9. Epithelially expressed Fgf9 interacts with its receptors (Fgfr1 and Fgfr2) on mesenchymal stem cells. These cells in turn express inhibitors of Tgfβ signaling that interact with mesenchymal fibroblasts to inhibit their expression of {alpha}-SMA.