Fig. 8. mil requires PI3K to modulate cell motility and process
formation but not directionality. (A,B) The orientation and
length of cellular processes of WT embryos injected with 250 pg dn-PI3K alone
(A) or with 4.3 ng mil-MO (B). The morphology of the cells is
highlighted in the insets. The length of the long axis of cells and their
orientation with respect to the direction of movement (y-axis) were
calculated and plotted, the angle from the y-axis was calculated as
cosine. (C) Summary of analysis of parameters: speed, persistence and
coherence. Statistically significant differences are indicated
(#P<0.05 and ##P<0.005).