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Figure 8


Fig. 8. mil requires PI3K to modulate cell motility and process formation but not directionality. (A,B) The orientation and length of cellular processes of WT embryos injected with 250 pg dn-PI3K alone (A) or with 4.3 ng mil-MO (B). The morphology of the cells is highlighted in the insets. The length of the long axis of cells and their orientation with respect to the direction of movement (y-axis) were calculated and plotted, the angle from the y-axis was calculated as cosine. (C) Summary of analysis of parameters: speed, persistence and coherence. Statistically significant differences are indicated (#P<0.05 and ##P<0.005).