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Figure 7


Fig. 7. Numb and Spdo localization during MP divisions. Confocal images of MP1 and MP4 divisions in sim-Gal4 UAS-tau-GFP (green) stage 11 Drosophila embryos stained with (A-F) anti-Numb (magenta) and (G-L) anti-Spdo (magenta). Sagittal views with anterior left and internal (basal) up. White arrowheads indicate: (A,B,G,H) MP4, (C,D) Numb+ VUM4 neuron, (I,J) basal VUM4 neuron with cytoplasmic punctate Spdo, (E,K) MP1 and (F,L) MP1 neurons. Yellow arrowheads indicate: (C,D) Numb- VUM4 neuron, (I) apical VUM4 neuron with cytoplasmic punctate Spdo and (J) membranous Spdo VUM4 neuron.