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Figure 1


Fig. 1. The sq181 mutation confers a liverless phenotype. Wild-type (wt) and mutant (mu) zebrafish embryos at 3 dpf were harvested for WISH. (A,B) Lateral view using the liver-specific markers (A) prox1 and (B) lfabp. (C,D) Dorsal view using (C) a trypsin probe for the exocrine pancreas and (D) an insulin probe for the islet. (E,F) Dorsal view using (E) an ifabp probe for the intestine and (F) a foxa3 probe for the entire digestive system. Black arrows, liver; red arrows, exocrine pancreas; black arrowheads, islet; blue arrows, intestine.