Fig. 1. Ectopic poles in the equatorial region of meiotic metaphase spindle in the Drosophila incenp mutant. Metaphase I-arrested oocytes from wild type (A) and the incenp^QA26 mutant (B,C) were immunostained for DNA, tubulin and the pole protein D-TACC. Ectopic poles, which often accumulate D-TACC, were formed in the incenp mutant. (D) Frequencies of abnormal morphology of meiotic spindles in wild type and the incenp mutant. More than 30 spindles were examined. The difference is significant (P<0.001). Scale bar: 10 µm.