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Figure 1


Fig. 1. Expression of TSHZ3 in the developing ureter and metanephros. (A-C) Immunostaining for TSHZ3 (green) and PAX2 (red) that visualises the UB and metanephric mesenchyme (mm) at E11.5 (A), E12.5 (B) and E12.75 (C). (D-H) Immunostaining for TSHZ3 (green) and nuclei (DAPI, blue) at E15.5 in metanephros (D), ureter (E) and bladder (F) and at E18.5 in ureter (G) and the bladder (H). Broken line in H separates the submucosal layer and the detrusor. d, detrusor SM; e, epithelium; mm, metanephric mesenchyme; mms, metanephric medullary stroma; pUB, proximal ureteric bud; sl, submucosal layer; UBs, ureteric bud stalk.