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Figure 4


Fig. 4. Neurod1 activates early markers of RGC differentiation in the absence of Math5. (A-D3) Immunostaining of retinas from E13.5 embryos with anti-Pou4f2/Brn3b (A-D), anti-Isl1 (A1-D1), merged Pou4f2-Isl1 images (A2-D2) and anti-NF160 (A3-D3). Insets show higher magnification of indicated areas. (A-A3) Math5lacZ-KI/+, (B-B3) Math5lacZ-KI/lacZ-KI, (C-C3) Math5Neurod1-KI/Math3-KI and (D-D3) Math5Neurod1-KI/lacZ-KI. Scale bar: 100 µm.