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Figure 6


Fig. 6. Neurod1 and Math3 activate the RGC gene regulatory network in the absence of Math5. Math5Neurod1-KI/Math3-KI retinas from E14.5 (or E13.5 for G1,G2) embryos were analyzed by in situ hybridization (purple) or immunostaining (green). (A1-H1) Wild-type retinas. (A2-H2) Math5Neurod1-KI/Math3-KI retinas. In situ hybridization probes and antibodies for immunostaining representing genes downstream of Math5 are indicated in the lower left-hand corner in A1-H1.