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Figure 8


Fig. 8. Transcriptional activation of Cdk1 in adult tissues. (A-H) The organs from four Cdk2+/+ Cdk1+/Cdk2KI mice were collected, sectioned and stained. H&E (A'-H') and β-galactosidase (A''-H'') staining patterns in brain (A), heart (B), skin (C), kidney (D), lung (E) thymus (F), spleen (G) and testes (H). (I) Western blot showing the expression level of knockin HA-Cdk2 (upper panel) and endogenous Cdk2 (bottom panel) in various adult organs collected from Cdk2+/+ Cdk1+/Cdk2KI mice. Scale bars: 100 µm, except 250 µm in H',H''.