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Figure 1


Fig. 1. Defects of the NCC-specific Pofut1-knockout mouse. (A) External morphology of control and Pofut1 cKO mice at postnatal day 1 (P1). The Pofut1 cKO mouse is relatively small, but otherwise shows no apparent morphological defects. Arrowheads indicate the stomach. (B-E) Immunostaining of the gastrointestinal tract at E16.5 in control (B,C) and Pofut1 cKO (D,E) embryos with the anti-neurofilament antibody 2H3.