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Figure 5


Fig. 5. Downregulation of Sox10 in Pofut1-null ENCCs. (A-H) Immunohistological detection of Sox10 (red) expression within ENCCs (green) in control (A-D) and Pofut1 cKO (E-H) mouse embryos at E10.5 (A,B,E,F) and E11.5 (C,D,G,H). (I,J) Quantitation of Sox10-positive cells at E10.5 (I) and E11.5 (J). Average percentages of Sox10-positive ENCC cells are shown with s.d. (K) Quantification of the proliferation rate in Sox10-positive ENCCs at E11.5. Average percentages of BrdU incorporation in proliferating Sox10-positive ENCC cells are shown with s.d. ns, not significant.