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Figure 4


Fig. 4. Dkk1 is a downstream target of the GATA4-FOG2 transcription complex. (A,B) qRT-PCR analysis of Dkk1 expression was performed with wild-type (A) or wild-type and Fog2-/- (B) gonad-mesonephros samples. (C-L) ISH was performed with a Dkk1 RNA probe on XX and XY gonads from wild-type, Gata4ki/ki and Fog2-/- E11.5-13.5 mouse embryos as indicated.