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Figure 2


Fig. 2. Fab-7 is able to substitute for Fab-8. (A-D) Cuticles were prepared from adult homozygous females of the indicated genotypes [see Mihaly et al. (Mihaly et al., 1997) for a detailed description of cuticular phenotypes]. (A) Wild-type: A8 does not contribute to any visible tergite or sternite structure in the adult female. The A7 sternite (ventral) displays a characteristic shape with large bristles pointing towards the posterior (arrow). (B) Fab-8305: the A7 to A8 transformation leads to the absence or reduction of the tergite (dorsal) and sternite (ventral). (C) F8->F7 homozygous females display a wild-type A7 cuticle. (D) Diagram of F8->F7 substitution. (E-G) Abd-B expression in the embryonic CNS. (E) Wild-type: Abd-B is expressed in a step gradient pattern from PS10 to PS14. (F) Fab-8305: the Abd-B expression level in PS12 increases to the level normally observed in PS13. (G) F8->F7 embryos show a restoration of the wild-type expression pattern of Abd-B.