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Figure 7


Fig. 7. Epistasis between Insm1, Phox2b and Mash1 in the differentiation of sympatho-adrenal precursor cells. Analysis of the primary sympathetic ganglion chain in wild-type (A,B), Phox2b (C,D) and Mash1 (E,F) mutant mice at E10.5 (A,C,E) and E12.5 (B,D,F) by in situ hybridization using a probe specific for Insm1. (G) Schematic drawing of the epistatic relationship between Mash1, Phox2b and Insm1. Scale bars: 100 µm in A,B.