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Figure 7


Fig. 7. Asymmetric gonad development in sexually differentiating chick embryos. Expression domains of PITX2c, Ad4BP/SF-1, RALDH2, ER{alpha} and cyclin D1 before sexual differentiation (stages 18 and 27) in the chick embryonic gonad, along with expression patterns of aromatase and ER{alpha} at sex-determined stages (stages 29 and 30) in the female chick embryonic gonad are illustrated. The events shown in the sex-independent process occur in both sexes. L-R differential genetic and functional cascades are indicated at stage 27, in accordance with our findings. The genes in black and gray are expressed and suppressed genes, respectively.