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Figure 8


Fig. 8. Cux2 and V2 interneuron formation. (A,B) Expression of homeodomain transcription factor Chx10 in V2 interneurons in the spinal cords of E10.5 wild-type (A) and Cux2neo/neo (B) embryos. (C) Cux2neo/neo mutants (n=8; 9.25±5.09) displayed a 45% decrease (P=0.002) in Chx10-positive V2 interneurons relative to controls (n=5; 20.40±5.03). The average values of Chx10-positive cells were plotted with error bars reflecting the standard deviation from the mean.