Fig. 5. Maternal expression of Groucho or its derivatives does not disrupt
embryonic anteroposterior axis formation. The anterior localisation of
hb (A-D) and posterior localisation of nos
(E-H) RNA transcripts, as well as the degradation of the Cic protein at
the termini (I-L) are indistinguishable in early stage 5 control
embryos (A,E,I) and in embryos maternally expressing Gro (B,F,J) or its
variants, GroAA (C,G,K) and GroDD (D,H,L). By contrast,
the posterior zygotic hb stripe is derepressed posteriorly in Gro (B)
and GroAA (C), but not in GroDD (D)-expressing embryos.
hb is not derepressed in a ventroposterior domain in Gro (B) and
GroAA (C) expressing embryos (white arrows), in accordance with the
enduring hkb expression in these embryos (see
Fig. 4F,G). (A-D,I-L) Black
arrows indicate the same relative positions in all embryos.