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Figure 5


Fig. 5. dFMRP overexpression abrogates normal MB neuronal development. (A) Developmental profile of axon projections of single-cell MARCM gamma neuron clones overexpressing dFMRP. Boxed insets highlight presynaptic branches that are pruned (arrows). Scale bar: 10 µm. (B) Quantitation of total axon branch number of dFMRP-overexpressing MARCM clones. Each point is data from a single-cell MARCM clone. Horizontal lines represent the mean for each data set. *0.01<P<0.05. P3, 60-70 hours APF; P4, 88-96 hours APF; 0-3h, 0-3 hours AE; 4d, 96-112 hours AE.