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Figure 2


Fig. 2. Asymmetric expression of Nodal pathway components is unaffected by the fby mutation. (A,B,F,G) The lateral plate mesoderm and (C-E,H-J) the dorsal diencephalon of 20-hpf zebrafish embryos. All views are dorsal, except for frontal views in E and J. Left-sided expression of the Nodal-related genes southpaw (spaw; A,F) and cyclops (cyc; C,H), the Nodal antagonist lefty1 (lft1; B,D,G,I), and of the downstream Nodal effector pitx2 (E,J) was observed in both WT and fby mutant embryos during somitogenesis. Scale bars: 25 µm.