Fig. 5. Changes in the number of DRG neuron subtypes in Runx3^-/- mice. (A-G) Immunoreactivity (brown) of Vglut1 (A',A''), TrkA (B',B''), TrkB (C',C''), c-Ret (D',D''), calbindin-28K (CB; E',E''), somatostatin (SOM; F',F'') and CGRP (G',G'') in wild-type (A'-G') and Runx3^-/- (A''-G'') mice. Boxed areas of immunoreactive neurons are shown at higher magnification in the insets at the left bottom of each panel. (A'''-G''') Quantification of the number of DRG neuron subtypes in wild-type (white bars) and Runx3^-/- (black bars) mice. Data are shown as mean ±s.e.m.; ^*P<0.05, ^**P<0.001. Scale bar: 100 µm.