Fig. 6. Defects in the stria vascularis of Tbx18KO mice. (A-L) Detection of strial proteins by immunofluorescence on midmodiolar sections of cochleae of control and Tbx18KO mice at P21. Figures show the stria vascularis in the basal turn. Antibodies against proteins of marginal, intermediate and basal cells, as well as of basement membrane components, were used as indicated in the figure. (C-F) Immunofluorescence on DAPI-counterstained sections detected by laser scanning microscopy. Insets show higher magnifications of the stria vascularis at regions indicated by rectangles in the figures, and reveal the disturbed formation of cellular processes by marginal cells (C,D) and intermediate cells (E,F). (M) Schematic summary of expression domains and model of the stria vascularis of wild-type and Tbx18KO mice.