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Figure 1


Fig. 1. Modulation of hipk affects wing development. (A) Wild-type wing. (B,C) Reducing hipk function by generating somatic hipk4 clones (B) or through expression of UAS-hipk-RNAi in the wing with sd-gal4 (C) both led to the loss of the wing margin (arrow). (D,E) Overexpression of hipk in the wing blade with the omb-gal4 driver caused the formation of an additional wing margin (D) and outgrowths from the ventral side of the wing (E). (F) Misexpressing two copies of hipk led to the formation of additional wing tissue outgrowths.