Fig. 2. Increasing the levels of Hipk can compensate for the loss of the Wg signaling. (A) Wild-type wing. (B) UAS-hipk/69B-Gal4. (C,D) Misexpression of hipk produced a mild ectopic vein phenotype similar to what is seen with UAS-arm^S10/+; bs-gal4/+ (C) or nmo^DB24/nmo^adk(D). (E) The hypomorphic wg allelic combination wg¹/wg^1-17 caused a wing-to-notum transformation, which was rescued by co-expression of hipk (F). (G) UAS-DFz2N33/+; 69B-Gal4/+ causes a severely notched wings. (H) UAS-DFz2N33/+; 69B/UAS-hipk. Simultaneously misexpressing hipk rescued the loss of wing tissue caused by ectopic expression of DFz3N33. (I) UAS-DFz2N33/+; dpp-Gal4/+. (J) UAS-DFz2N33/+; dpp-Gal4/hipk⁴. (K) sd>DAxin causes mild notches and loss of posterior margin bristles that are enhanced by loss of one copy of hipk in 32B>Daxin, hipk³/+ (L).