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Development, Vol 102, Issue 3 489-497, Copyright © 1988 by Company of Biologists
JOURNAL ARTICLES |
NE Baker
Department of Biochemistry, University of California, Berkeley, 94720.
Wingless (wg) is a segment-polarity gene in Drosophila which is related to the murine proto-oncogene int1. In Drosophila embryos, wg transcription defines part of each parasegment. In situ hybridization shows that wg is also expressed in the imaginal discs which give rise to the adult during metamorphosis. Transcripts are localized in the apical cytoplasm of disc cells, and accumulate in different patterns in dorsal and ventral discs. The wgCX3 mutation produces morphological defect in the adult structures derived from these imaginal discs. The results show that wg is involved in the development of the adult, as well as the embryo, but that the imaginal discs do not express this segment-polarity gene in an identical pattern to the embryonic segments.
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J. Couso, M Bate, and A Martinez-Arias A wingless-dependent polar coordinate system in Drosophila imaginal discs Science, January 22, 1993; 259(5094): 484 - 489. [Abstract] [PDF]
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J. Williams, S. Paddock, and S. Carroll Pattern formation in a secondary field: a hierarchy of regulatory genes subdivides the developing Drosophila wing disc into discrete subregions Development, January 2, 1993; 117(2): 571 - 584. [Abstract] [PDF]
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