spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Riou, J-F
Right arrow Articles by Boucaut, J-C
Right arrow Search for Related Content
PubMed
Right arrow Articles by Riou, J-F
Right arrow Articles by Boucaut, J-C
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?
Development, Vol 104, Issue 3 511-524 Copyright © 1988 by Company of Biologists

Journal Articles

Expression of tenascin in response to neural induction in amphibian embryos

J-F Riou, D-L Shi, M Chiquet, and J-C Boucaut

The expression of tenascin, a constituent of extracellular matrix (ECM), was studied during the embryonic development of the amphibian Pleurodeles waltl. An antiserum to chick fibroblast tenascin was shown to cross-react with the homologous molecule of the amphibian. Immunostaining of embryo sections with anti-tenascin antiserum revealed that tenascin appears just after the completion of neurulation. At the tailbud stage, tenascin is present in the ECM located at sites of directed cell migration (neural crest cell migration pathways, extension of the pronephretic duct) and mesenchyme condensation (endocardium, aortic arches). The accumulation of tenascin immunoreactivity in the embryonic ECM is correlated with the synthesis of the 220x103Mr polypeptide of the molecule. To provide data on the patterning of tenascin, ectoderm and dorsal blastoporal lip isolated at early gastrula stage were cultured for a period of 3 days. Epidermal vesicles differentiating from isolated ectoderm completely lack tenascin. Conversely, axial mesoderm derivatives present in cultured dorsal blastoporal lip were found to produce tenascin. Neural induction of ectoderm isolated at early gastrula stage was performed in vitro with the dorsal blastoporal lip or concanavalin A. The induced neural tissue was found to accumulate tenascin. Spemann experiments confirmed in vivo that tenascin is expressed by ectodermal cells as a response to neural induction.
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 J. Cell Sci.Home page
C. Chung and H. Erickson
Glycosaminoglycans modulate fibronectin matrix assembly and are essential for matrix incorporation of tenascin-C
J. Cell Sci., January 6, 1997; 110(12): 1413 - 1419.
[Abstract] [PDF]

Home page
 J. Biol. Chem.Home page
C. Y. Chung, L. Zardi, and H. P. Erickson
Binding of Tenascin-C to Soluble Fibronectin and Matrix Fibrils
J. Biol. Chem., December 1, 1995; 270(48): 29012 - 29017.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
M Umbhauer, J. Riou, J Spring, J. Smith, and J. Boucaut
Expression of tenascin mRNA in mesoderm during Xenopus laevis embryogenesis: the potential role of mesoderm patterning in tenascin regionalization
Development, January 9, 1992; 116(1): 147 - 157.
[Abstract] [PDF]


© The Company of Biologists Ltd 1988