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Development, Vol 105, Issue 4 733-737, Copyright © 1989 by Company of Biologists
JOURNAL ARTICLES |
RS Beddington and EJ Robertson
ICRF Developmental Biology Unit, Department of Zoology, Oxford, UK.
Embryonic stem cells (ES) cells were injected into host blastocysts either in groups of 10-15 cells or as single cells in order to test their developmental potential in the developing embryo. The analysis of midgestation chimaeras, by electrophoretic separation of glucose phosphate isomerase (GPI) isozymes, showed that ES cells were capable of colonizing trophectoderm and primitive endoderm derivatives at a low frequency, as well as producing a high rate of chimaerism in tissues of the fetus and extraembryonic mesoderm.
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Z. Gu, M. Nomura, B. B. Simpson, H. Lei, A. Feijen, J. van den Eijnden-van Raaij, P. K. Donahoe, and E. Li The type I activin receptor ActRIB is required for egg cylinder organization and gastrulation in the mouse Genes & Dev., March 15, 1998; 12(6): 844 - 857. [Abstract] [Full Text]
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I Dragatsis, A Efstratiadis, and S Zeitlin Mouse mutant embryos lacking huntingtin are rescued from lethality by wild-type extraembryonic tissues Development, January 4, 1998; 125(8): 1529 - 1539. [Abstract] [PDF]
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M Rhinn, A Dierich, W Shawlot, R. Behringer, M Le Meur, and S. Ang Sequential roles for Otx2 in visceral endoderm and neuroectoderm for forebrain and midbrain induction and specification Development, January 3, 1998; 125(5): 845 - 856. [Abstract] [PDF]
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