|
|
|
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
Development, Vol 109, Issue 4 911-923, Copyright © 1990 by Company of Biologists
JOURNAL ARTICLES |
A Orr-Urtreger, A Avivi, Y Zimmer, D Givol, Y Yarden and P Lonai
Department of Chemical Immunology, Weizmann Institute of Science, Rehovot, Israel.
Developmental expression of the c-kit proto-oncogene, a receptor tyrosine kinase encoded by the W locus, was investigated by in situ hybridization in normal mouse embryos. Early after implantation transcripts were detectable only in the maternal placenta (6 1/2-7 1/2 days p.c.). Subsequently (8 1/2 days p.c.) numerous ectodermal (neural tube, sensory placodes) and endodermal (embryonic gut) derivatives expressed c-kit. Later transcripts were detected also in the blood islands of the yolk sac and in the embryonic liver, the main sites of embryonic hemopoiesis. Around midgestation, transcripts accumulated in the branchial pouches and also in primordial germ cells of the genital ridges. This complex pattern of expression remained characteristic also later in gestation, when c-kit was expressed in highly differentiated structures of the craniofacial area, in presumptive melanoblasts and in the CNS. In the adult ovary, maternal c-kit transcripts were detected. They were present in the oocytes of both immature and mature ovarian follicles, but not in the male germ line, where c-kit expression may be down regulated. Thus, c-kit activity is complex and appears in multiple tissues including those that also display defects in mutations at the W locus where c-kit is encoded. Correlation between W phenotypes and c-kit expression, as well as the regulation of the complex and multiple expression of polypeptide growth factors and receptors, is discussed.
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati 
Twitter What's this?
This article has been cited by other articles:
|
|
 |
|
  S. Mithraprabhu and K. L Loveland Control of KIT signalling in male germ cells: what can we learn from other systems? Reproduction, November 1, 2009; 138(5): 743 - 757. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. Adhikari and K. Liu Molecular Mechanisms Underlying the Activation of Mammalian Primordial Follicles Endocr. Rev., August 1, 2009; 30(5): 438 - 464. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. H Thomas, R. S Ismail, J.-Y. Jiang, and B. C Vanderhyden Kit Ligand 2 Promotes Murine Oocyte Growth In Vitro Biol Reprod, January 1, 2008; 78(1): 167 - 175. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. Liu, S. Rajareddy, P. Reddy, K. Jagarlamudi, C. Du, Y. Shen, Y. Guo, K. Boman, E. Lundin, U. Ottander, et al. Phosphorylation and inactivation of glycogen synthase kinase-3 by soluble kit ligand in mouse oocytes during early follicular development J. Mol. Endocrinol., January 1, 2007; 38(1): 137 - 146. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W.-L. Li, Y. Yamada, M. Ueno, S. Nishikawa, S.-I. Nishikawa, and N. Takakura Platelet Derived Growth Factor Receptor Alpha Is Essential for Establishing a Microenvironment That Supports Definitive Erythropoiesis J. Biochem., August 1, 2006; 140(2): 267 - 273. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. H. Thomas, J.-F. Ethier, S. Shimasaki, and B. C. Vanderhyden Follicle-Stimulating Hormone Regulates Oocyte Growth by Modulation of Expression of Oocyte and Granulosa Cell Factors Endocrinology, February 1, 2005; 146(2): 941 - 949. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Jarvis, D. J. Elliott, D. Morgan, R. Winston, and C. Readhead Molecular markers for the assessment of postnatal male germ cell development in the mouse Hum. Reprod., January 1, 2005; 20(1): 108 - 116. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Hachiya, A. Kobayashi, Y. Yoshida, T. Kitahara, Y. Takema, and G. Imokawa Biphasic Expression of Two Paracrine Melanogenic Cytokines, Stem Cell Factor and Endothelin-1, in Ultraviolet B-Induced Human Melanogenesis Am. J. Pathol., December 1, 2004; 165(6): 2099 - 2109. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Shimasaki, R. K. Moore, F. Otsuka, and G. F. Erickson The Bone Morphogenetic Protein System In Mammalian Reproduction Endocr. Rev., February 1, 2004; 25(1): 72 - 101. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Ohta, A. Tohda, and Y. Nishimune Proliferation and Differentiation of Spermatogonial Stem Cells in the W/Wv Mutant Mouse Testis Biol Reprod, December 1, 2003; 69(6): 1815 - 1821. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Terada, S. Ueno, K. Yomogida, T. Imai, H. Kiyonari, N. Takeda, M. Yano, S. Abe, S. Aizawa, and M. Mori Expression of Tom34 Splicing Isoforms in Mouse Testis and Knockout of Tom34 in Mice J. Biochem., May 1, 2003; 133(5): 625 - 631. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. J. Meeks, S. E. Crawford, T. A. Russell, K.-i. Morohashi, J. Weiss, and J. L. Jameson Dax1 regulates testis cord organization during gonadal differentiation Development, March 1, 2003; 130(5): 1029 - 1036. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Sotlar, L. Escribano, O. Landt, S. Mohrle, S. Herrero, A. Torrelo, U. Lass, H.-P. Horny, and B. Bultmann One-Step Detection of c-kit Point Mutations Using Peptide Nucleic Acid-Mediated Polymerase Chain Reaction Clamping and Hybridization Probes Am. J. Pathol., March 1, 2003; 162(3): 737 - 746. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Perez-Losada, M. Sanchez-Martin, A. Rodriguez-Garcia, M. L. Sanchez, A. Orfao, T. Flores, and I. Sanchez-Garcia Zinc-finger transcription factor Slug contributes to the function of the stem cell factor c-kit signaling pathway Blood, July 30, 2002; 100(4): 1274 - 1286. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. Otsuka and S. Shimasaki A negative feedback system between oocyte bone morphogenetic protein 15 and granulosa cell kit ligand: Its role in regulating granulosa cell mitosis PNAS, June 11, 2002; 99(12): 8060 - 8065. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. C. Eckery, S. B. Lawrence, J. L. Juengel, P. Greenwood, K. P. McNatty, and A. E. Fidler Gene Expression of the Tyrosine Kinase Receptor c-kit During Ovarian Development in the Brushtail Possum (Trichosurus vulpecula) Biol Reprod, February 1, 2002; 66(2): 346 - 353. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. M. Ward and K. M. Sanders Physiology and Pathophysiology of the Interstitial Cell of Cajal: From Bench to Bedside: I. Functional development and plasticity of interstitial cells of Cajal networks Am J Physiol Gastrointest Liver Physiol, September 1, 2001; 281(3): G602 - G611. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Okamura, A. Myoumoto, N. Manabe, N. Tanaka, H. Okamura, and M. Fukumoto Protein tyrosine kinase expression in the porcine ovary Mol. Hum. Reprod., August 1, 2001; 7(8): 723 - 729. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Krishnamurthy, P. Suresh Babu, C. R. Morales, and M. R. Sairam Delay in Sexual Maturity of the Follicle-Stimulating Hormone Receptor Knockout Male Mouse Biol Reprod, August 1, 2001; 65(2): 522 - 531. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. A. Flaws, A. N. Hirshfield, J. A. Hewitt, J. K. Babus, and P. A. Furth Effect of Bcl-2 on the Primordial Follicle Endowment in the Mouse Ovary Biol Reprod, April 1, 2001; 64(4): 1153 - 1159. [Abstract] [Full Text]
|
|
|
|
 |
|
 K Sotlar, T Marafioti, H Griesser, J Theil, C Aepinus, R Jaussi, H Stein, P Valent, and H-P Horny Detection of c-kit mutation Asp 816 to Val in microdissected bone marrow infiltrates in a case of systemic mastocytosis associated with chronic myelomonocytic leukaemia Mol. Pathol., August 1, 2000; 53(4): 188 - 193. [Abstract] [Full Text]
|
|
|
|
|
|
K. Kato, A. M. Morrison, T. Nakano, K. Tashiro, and T. Honjo ESOP-1, a secreted protein expressed in the hematopoietic, nervous, and reproductive systems of embryonic and adult mice Blood, July 1, 2000; 96(1): 362 - 364. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Ohta, K. Yomogida, K. Dohmae, and Y. Nishimune Regulation of proliferation and differentiation in spermatogonial stem cells: the role of c-kit and its ligand SCF Development, May 15, 2000; 127(10): 2125 - 2131. [Abstract] [PDF]
|
|
|
|
|
|
T. Shinohara, M. R. Avarbock, and R. L. Brinster beta 1- and alpha 6-integrin are surface markers on mouse spermatogonial stem cells PNAS, May 11, 1999; 96(10): 5504 - 5509. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Parichy, J. Rawls, S. Pratt, T. Whitfield, and S. Johnson Zebrafish sparse corresponds to an orthologue of c-kit and is required for the morphogenesis of a subpopulation of melanocytes, but is not essential for hematopoiesis or primordial germ cell development Development, January 8, 1999; 126(15): 3425 - 3436. [Abstract] [PDF]
|
|
|
|
|
|
N. R. Leslie, J. O'Prey, C. Bartholomew, and P. R. Harrison An Activating Mutation in the Kit Receptor Abolishes the Stroma Requirement for Growth of ELM Erythroleukemia Cells, But Does Not Prevent Their Differentiation in Response to Erythropoietin Blood, December 15, 1998; 92(12): 4798 - 4807. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. A. Parrott and M. K. Skinner Thecal Cell-Granulosa Cell Interactions Involve a Positive Feedback Loop among Keratinocyte Growth Factor, Hepatocyte Growth Factor, and Kit Ligand during Ovarian Follicular Development Endocrinology, May 1, 1998; 139(5): 2240 - 2245. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T Kunisada, H Yoshida, H Yamazaki, A Miyamoto, H Hemmi, E Nishimura, L. Shultz, S Nishikawa, and S Hayashi Transgene expression of steel factor in the basal layer of epidermis promotes survival, proliferation, differentiation and migration of melanocyte precursors Development, January 8, 1998; 125(15): 2915 - 2923. [Abstract] [PDF]
|
|
|
|
|
|
J. A. Parrott and M. K. Skinner Direct Actions of Kit-Ligand on Theca Cell Growth and Differentiation During Follicle Development Endocrinology, September 1, 1997; 138(9): 3819 - 3827. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. C. Broudy Stem Cell Factor and Hematopoiesis Blood, August 15, 1997; 90(4): 1345 - 1364. [Full Text] [PDF]
|
|
|
|
|
|
A. Amsterdam and N. Selvaraj Control of Differentiation, Transformation, and Apoptosis in Granulosa Cells by Oncogenes, Oncoviruses, and Tumor Suppressor Genes Endocr. Rev., August 1, 1997; 18(4): 435 - 461. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Gnessi, A. Fabbri, and G. Spera Gonadal Peptides as Mediators of Development and Functional Control of the Testis: An Integrated System with Hormones and Local Environment Endocr. Rev., August 1, 1997; 18(4): 541 - 609. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. L. Miller, V. I. Rebel, C. D. Helgason, P. M. Lansdorp, and C. J. Eaves Impaired Steel Factor Responsiveness Differentially Affects the Detection and Long-Term Maintenance of Fetal Liver Hematopoietic Stem Cells In Vivo Blood, February 15, 1997; 89(4): 1214 - 1223. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M Kluppel, D. Nagle, M Bucan, and A Bernstein Long-range genomic rearrangements upstream of Kit dysregulate the developmental pattern of Kit expression in W57 and Wbanded mice and interfere with distinct steps in melanocyte development Development, January 1, 1997; 124(1): 65 - 77. [Abstract] [PDF]
|
|
|
|
|
|
F Bernex, P De Sepulveda, C Kress, C Elbaz, C Delouis, and J. Panthier Spatial and temporal patterns of c-kit-expressing cells in WlacZ/+ and WlacZ/WlacZ mouse embryos Development, January 10, 1996; 122(10): 3023 - 3033. [Abstract] [PDF]
|
|
|
|
|
|
L Lecoin, G Gabella, and N Le Douarin Origin of the c-kit-positive interstitial cells in the avian bowel Development, January 3, 1996; 122(3): 725 - 733. [Abstract] [PDF]
|
|
|
|
 |
|
 M A Bedell, C I Brannan, E P Evans, N G Copeland, N A Jenkins, and P J Donovan DNA rearrangements located over 100 kb 5' of the Steel (Sl)-coding region in Steel-panda and Steel-contrasted mice deregulate Sl expression and cause female sterility by disrupting ovarian follicle development. Genes & Dev., February 15, 1995; 9(4): 455 - 470. [Abstract] [PDF]
|
|
|
|
|
|
B Wehrle-Haller and J. Weston Soluble and cell-bound forms of steel factor activity play distinct roles in melanocyte precursor dispersal and survival on the lateral neural crest migration pathway Development, January 3, 1995; 121(3): 731 - 742. [Abstract] [PDF]
|
|
|
|
|
|
C. Erickson and T. Goins Avian neural crest cells can migrate in the dorsolateral path only if they are specified as melanocytes Development, January 3, 1995; 121(3): 915 - 924. [Abstract] [PDF]
|
|
|
|
|
|
T Hirata, E Morii, M Morimoto, T Kasugai, T Tsujimura, S Hirota, Y Kanakura, S Nomura, and Y Kitamura Stem cell factor induces outgrowth of c-kit-positive neurites and supports the survival of c-kit-positive neurons in dorsal root ganglia of mouse embryos Development, January 9, 1993; 119(1): 49 - 56. [Abstract] [PDF]
|
|
|
|
|
|
M Pesce, M. Farrace, M Piacentini, S Dolci, and M De Felici Stem cell factor and leukemia inhibitory factor promote primordial germ cell survival by suppressing programmed cell death (apoptosis) Development, January 8, 1993; 118(4): 1089 - 1094. [Abstract] [PDF]
|
|
|
|
|
|
M Ogawa, S Nishikawa, K Yoshinaga, S Hayashi, T Kunisada, J Nakao, T Kina, T Sudo, H Kodama, and S Nishikawa Expression and function of c-Kit in fetal hemopoietic progenitor cells: transition from the early c-Kit-independent to the late c-Kit-dependent wave of hemopoiesis in the murine embryo Development, January 3, 1993; 117(3): 1089 - 1098. [Abstract] [PDF]
|
|
|
|
|
|
A Orr-Urtreger and P Lonai Platelet-derived growth factor-A and its receptor are expressed in separate, but adjacent cell layers of the mouse embryo Development, January 8, 1992; 115(4): 1045 - 1058. [Abstract] [PDF]
|
|
|
|
|
|
K. Steel, D. Davidson, and I. Jackson TRP-2/DT, a new early melanoblast marker, shows that steel growth factor (c-kit ligand) is a survival factor Development, January 8, 1992; 115(4): 1111 - 1119. [Abstract] [PDF]
|
|
|
|
|
|
R Palacios and S Nishikawa Developmentally regulated cell surface expression and function of c-kit receptor during lymphocyte ontogeny in the embryo and adult mice Development, January 8, 1992; 115(4): 1133 - 1147. [Abstract] [PDF]
|
|
|
|
|
|
P Ray, K M Higgins, J C Tan, T Y Chu, N S Yee, H Nguyen, E Lacy, and P Besmer Ectopic expression of a c-kitW42 minigene in transgenic mice: recapitulation of W phenotypes and evidence for c-kit function in melanoblast progenitors. Genes & Dev., December 1, 1991; 5(12a): 2265 - 2273. [Abstract] [PDF]
|
|
|
|
|
|
R M Schmitt, E Bruyns, and H R Snodgrass Hematopoietic development of embryonic stem cells in vitro: cytokine and receptor gene expression. Genes & Dev., May 1, 1991; 5(5): 728 - 740. [Abstract] [PDF]
|
|
