spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Williams, N. E.
Right arrow Articles by Kaczanowska, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Williams, N. E.
Right arrow Articles by Kaczanowska, J.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Development, Vol 109, Issue 4 935-942, Copyright © 1990 by Company of Biologists

JOURNAL ARTICLES

The formation of basal body domains in the membrane skeleton of Tetrahymena

NE Williams, JE Honts and J Kaczanowska
Department of Biology, University of Iowa, Iowa City 52242.

Differentiated regions within the membrane skeleton are described around basal bodies in the ciliary rows of Tetrahymena. These domains, approximately 1 micron in diameter, are characterized by a relatively dense ultrastructure, the presence of a family of proteins called K antigens (Mr 39-44 x 10(3)) that are recognized by mAb 424A8, and the apparent exclusion of major membrane skeleton proteins that are present in most other regions of the cell (Mr 135, 125 x 10(3]. Mature basal body domains are asymmetric, reflecting the polarity of the cell as a whole. A similar differentiation of the membrane skeleton occurs in the oral apparatus, except here the K antigens surround four clusters of basal bodies (from which this cell takes its name) rather than the individual basal bodies. The development of new basal body domains in the cell cycle is described, with similarities and differences noted between somatic and oral regions of the cell. It is concluded that the capacity of this cell for precise topographic regulation of molecular events in the membrane skeleton makes it a useful model for the study of cortical differentiation in cells generally.
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 Mol. Biol. CellHome page
C. G. Pearson, T. H. Giddings Jr., and M. Winey
Basal Body Components Exhibit Differential Protein Dynamics during Nascent Basal Body Assembly
Mol. Biol. Cell, February 1, 2009; 20(3): 904 - 914.
[Abstract] [Full Text] [PDF]

Home page
 Eukaryot CellHome page
J. Frankel
What Do Genic Mutations Tell Us about the Structural Patterning of a Complex Single-Celled Organism?
Eukaryot. Cell, October 1, 2008; 7(10): 1617 - 1639.
[Full Text] [PDF]

Home page
 JCBHome page
Y. Shang, C.-C. Tsao, and M. A. Gorovsky
Mutational analyses reveal a novel function of the nucleotide-binding domain of {gamma}-tubulin in the regulation of basal body biogenesis
J. Cell Biol., December 19, 2005; 171(6): 1035 - 1044.
[Abstract] [Full Text] [PDF]


© The Company of Biologists Ltd 1990