|
|
|
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
Development, Vol 111, Issue 3 829-844, Copyright © 1991 by Company of Biologists
JOURNAL ARTICLES |
B Angres, AH Muller, J Kellermann and P Hausen
Max Planck Institut fur Entwicklungsbiologie, Tubingen, Federal Republic of Germany.
Using a cadherin fraction from Xenopus tissue culture cells as an immunogen, two monoclonal antibodies were obtained that allowed the characterization of two distinct cadherins in the Xenopus embryo. The two cadherins differ in molecular weight, in their time of appearance during development and in their spatial pattern of expression. One of the antigens was identified as E-cadherin. It appears in the embryonic ectoderm during gastrulation when epidermal differentiation commences and it disappears from the neural plate area upon neural induction. The second antigen could not be allocated to any of the known cadherin subtypes and was termed U-cadherin. It is present in the egg and becomes deposited in newly formed inner cell membranes during cleavage, the outer apical membranes of the embryo remaining devoid of the cadherin throughout development. U-cadherin is found on membranes of all cells up to the late neurula stages. A conspicuous polarized expression of the antigen on the membranes of individual inner cells suggests its participation in the segregation of cell layers and organ anlagen. These findings are discussed in the context of current hypotheses on the role of cadherins in establishing the spatial structure of the embryo.
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati 
Twitter What's this?
This article has been cited by other articles:
|
|
 |
|
  W. El-Jouni, S. Haun, R. Hodeify, A. Hosein Walker, and K. Machaca Vesicular traffic at the cell membrane regulates oocyte meiotic arrest Development, September 15, 2007; 134(18): 3307 - 3315. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. D. Chalmers, M. Pambos, J. Mason, S. Lang, C. Wylie, and N. Papalopulu aPKC, Crumbs3 and Lgl2 control apicobasal polarity in early vertebrate development Development, March 1, 2005; 132(5): 977 - 986. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Cereijido, R. G. Contreras, and L. Shoshani Cell Adhesion, Polarity, and Epithelia in the Dawn of Metazoans Physiol Rev, October 1, 2004; 84(4): 1229 - 1262. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 X. Fang, H. Ji, S.-W. Kim, J.-I. Park, T. G. Vaught, P. Z. Anastasiadis, M. Ciesiolka, and P. D. McCrea Vertebrate development requires ARVCF and p120 catenins and their interplay with RhoA and Rac J. Cell Biol., April 12, 2004; 165(1): 87 - 98. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. D. Chalmers, B. Strauss, and N. Papalopulu Oriented cell divisions asymmetrically segregate aPKC and generate cell fate diversity in the early Xenopus embryo Development, June 15, 2003; 130(12): 2657 - 2668. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. V. Danilchik, S. D. Bedrick, E. E. Brown, and K. Ray Furrow microtubules and localized exocytosis in cleaving Xenopus laevis embryos J. Cell Sci., January 15, 2003; 116(2): 273 - 283. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Kofron, J. Heasman, S. A. Lang, and C. C. Wylie Plakoglobin is required for maintenance of the cortical actin skeleton in early Xenopus embryos and for cdc42-mediated wound healing J. Cell Biol., August 19, 2002; 158(4): 695 - 708. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. Leong, A. S. Menko, and G. B. Grunwald Differential Expression of N- and B-Cadherin during Lens Development Invest. Ophthalmol. Vis. Sci., October 1, 2000; 41(11): 3503 - 3510. [Abstract] [Full Text]
|
|
|
|
 |
|
 J. Cerdà, S. Reidenbach, S. Prätzel, and W. W. Franke Cadherin-Catenin Complexes During Zebrafish Oogenesis: Heterotypic Junctions Between Oocytes and Follicle Cells Biol Reprod, September 1, 1999; 61(3): 692 - 704. [Abstract] [Full Text]
|
|
|
|
 |
|
 S. Finnemann, I. Mitrik, M. Hess, G. Otto, and D. Wedlich Uncoupling of XB/U-Cadherin-Catenin Complex Formation from Its Function in Cell-Cell Adhesion J. Biol. Chem., May 2, 1997; 272(18): 11856 - 11862. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Damjanovski, X. Karp, S. Funk, E. H. Sage, and M. J. Ringuette Ectopic Expression of SPARC in Xenopus Embryos Interferes with Tissue Morphogenesis: Identification of a Bioactive Sequence in the C-terminal EF Hand J. Histochem. Cytochem., May 1, 1997; 45(5): 643 - 656. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Paul, K Yu, R Bruzzone, R. Gimlich, and D. Goodenough Expression of a dominant negative inhibitor of intercellular communication in the early Xenopus embryo causes delamination and extrusion of cells Development, January 2, 1995; 121(2): 371 - 381. [Abstract] [PDF]
|
|
|
|
|
|
F Fagotto and B. Gumbiner Beta-catenin localization during Xenopus embryogenesis: accumulation at tissue and somite boundaries Development, January 12, 1994; 120(12): 3667 - 3679. [Abstract] [PDF]
|
|
|
|
|
|
E Levine, C. Lee, C Kintner, and B. Gumbiner Selective disruption of E-cadherin function in early Xenopus embryos by a dominant negative mutant Development, January 4, 1994; 120(4): 901 - 909. [Abstract] [PDF]
|
|
|
|
|
|
J Heasman, D Ginsberg, B Geiger, K Goldstone, T Pratt, C Yoshida-Noro, and C Wylie A functional test for maternally inherited cadherin in Xenopus shows its importance in cell adhesion at the blastula stage Development, January 1, 1994; 120(1): 49 - 57. [Abstract] [PDF]
|
|
|
|
|
|
R. Mayor, L. J. Essex, M. F. Bennett, and M. G. Sargent Distinct elements of the xsna promoter are required for mesodermal and ectodermal expression Development, November 1, 1993; 119(3): 661 - 671. [Abstract] [PDF]
|
|
|
|
|
|
S Schneider, K Herrenknecht, S Butz, R Kemler, and P Hausen Catenins in Xenopus embryogenesis and their relation to the cadherin-mediated cell-cell adhesion system Development, January 6, 1993; 118(2): 629 - 640. [Abstract] [PDF]
|
|
|
|
 |
|
 C. Kintner Cadherins and the Morphogenesis of Epithelial Tissues in Xenopus Embryos Cold Spring Harb Symp Quant Biol, January 1, 1992; 57(0): 335 - 344. [Abstract] [PDF]
|
|
