|
|
|
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
Development, Vol 112, Issue 1 317-326, Copyright © 1991 by Company of Biologists
JOURNAL ARTICLES |
M Caizergues-Ferrer, C Mathieu, P Mariottini, F Amalric and F Amaldi
Centre de Recherche de Biochimie et de Genetique Cellulaires, CNRS, Toulouse, France.
Fibrillarin is one of the protein components that together with U3 snRNA constitute the U3 snRNP, a small nuclear ribonucleoprotein particle involved in ribosomal RNA processing in eucaryotic cells. Using an antifibrillarin antiserum for protein detection and a fibrillarin cDNA and a synthetic oligonucleotide complementary to U3 snRNA as hybridization probes, the expression of these two components has been studied during Xenopus development. Fibrillarin mRNA is accumulated early in oogenesis, like many other messengers, and translated during oocyte growth. Fibrillarin protein is thus progressively accumulated throughout oogenesis to be assembled with U3 snRNA and used for ribosome production in the amplified nucleoli. After fertilization, the amount of U3 snRNA decreases while the maternally accumulated fibrillarin mRNA is maintained and utilized to produce more protein. After the mid-blastula transition, stored fibrillarin is assembled with newly synthesized U3 snRNA and becomes localized in the prenucleolar bodies and reforming nucleoli.
This article has been cited by other articles:
|
|
 |
|
  H. Yang, J. Zhou, R. L. Ochs, D. Henning, R. Jin, and B. C. Valdez Down-regulation of RNA Helicase II/Gu Results in the Depletion of 18 and 28 S rRNAs in Xenopus Oocyte J. Biol. Chem., October 3, 2003; 278(40): 38847 - 38859. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R.D. Schramm, A. M. Paprocki, and C. A. VandeVoort Causes of developmental failure of in-vitro matured rhesus monkey oocytes: impairments in embryonic genome activation Hum. Reprod., April 1, 2003; 18(4): 826 - 833. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. D. Schramm and B. D. Bavister Onset of Nucleolar and Extranucleolar Transcription and Expression of Fibrillarin in Macaque Embryos Developing In Vitro Biol Reprod, March 1, 1999; 60(3): 721 - 728. [Abstract] [Full Text]
|
|
|
|
 |
|
 C. Verheggen, S. Le Panse, G. Almouzni, and D. Hernandez-Verdun Presence of Pre-rRNAs before Activation of Polymerase I Transcription in the Building Process of Nucleoli during Early Development of Xenopus laevis J. Cell Biol., September 7, 1998; 142(5): 1167 - 1180. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B A Peculis and J A Steitz Sequence and structural elements critical for U8 snRNP function in Xenopus oocytes are evolutionarily conserved. Genes & Dev., September 15, 1994; 8(18): 2241 - 2255. [Abstract] [PDF]
|
|
|
|
 |
|
 U Grossniklaus, K. Cadigan, and W. Gehring Three maternal coordinate systems cooperate in the patterning of the Drosophila head Development, January 11, 1994; 120(11): 3155 - 3171. [Abstract] [PDF]
|
|
|
|
 |
|
 M. Azum-Gelade, J Noaillac-Depeyre, M Caizergues-Ferrer, and N Gas Cell cycle redistribution of U3 snRNA and fibrillarin. Presence in the cytoplasmic nucleolus remnant and in the prenucleolar bodies at telophase J. Cell Sci., January 2, 1994; 107(2): 463 - 475. [Abstract] [PDF]
|
|
|
|
|
|
S J Baserga, M Gilmore-Hebert, and X W Yang Distinct molecular signals for nuclear import of the nucleolar snRNA, U3. Genes & Dev., June 1, 1992; 6(6): 1120 - 1130. [Abstract] [PDF]
|
|
