|
|
|
|||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
Development, Vol 114, Issue 4 997-1001, Copyright © 1992 by Company of Biologists
JOURNAL ARTICLES |
LJ Hagemann and NL First
Department of Scientific and Industrial Research, Palmerston North, New Zealand.
Androgenones (paternally derived genome) show a significant inability to form a blastocoele cavity. Eighty percent of these embryos die or arrest at earlier stages. Factor(s) from both normal and parthenogenetic late preimplantation embryos injected into each blastomere of androgenetic 4-cell stage can rescue more than twice as many to the blastocyst stage (47.2% versus 19.2% for non-injected androgenones). This factor(s) becomes available beginning at the 4-cell stage and is titratable. Injected total cytoplasmic mRNA will also cause a rescue response. Isolating this specific factor message(s) will permit the eventual cloning of possibly the earliest parentally imprinted gene(s) expressed during development.
This article has been cited by other articles:
![]() |
I. Lagutina, G. Lazzari, R. Duchi, and C. Galli Developmental Potential of Bovine Androgenetic and Parthenogenetic Embryos: A Comparative Study Biol Reprod, February 1, 2004; 70(2): 400 - 405. [Abstract] [Full Text] [PDF] |
||||
![]() |
Y. Obata, Y. Ono, H. Akuzawa, O.Y. Kwon, M. Yoshizawa, and T. Kono Post-implantation development of mouse androgenetic embryos produced by in-vitro fertilization of enucleated oocytes Hum. Reprod., April 1, 2000; 15(4): 874 - 880. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. Renard, P Baldacci, V Richoux-Duranthon, S Pournin, and C Babinet A maternal factor affecting mouse blastocyst formation Development, January 4, 1994; 120(4): 797 - 802. [Abstract] [PDF] |
||||