|
|
|
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
Development, Vol 118, Issue 2 427-438, Copyright © 1993 by Company of Biologists
JOURNAL ARTICLES |
RG Phillips and JR Whittle
School of Biological Sciences, University of Sussex, Brighton, UK.
We have used conditional wingless genotypes to dissect the role of this gene in late stages of wing disc development. One of these genotypes (wgIL/wg-lacZ) is simultaneously a reporter of wingless transcription and temperature-sensitive for wingless function, and has allowed us to define its pattern of transcription in the absence of wingless activity. The primordia of a subset of the bristles of the notum, which develop in or immediately adjacent to wingless-expressing cells, depend upon wingless activity. The time-course of this contribution and the effect on proneural gene expression together suggest that wingless may regulate the activity of products of the achaete-scute complex in proneural clusters. wingless activity is also required at the presumptive wing margin and is a necessary precondition for the change in proliferation pattern in this region. The involvement of wingless in transducing or mediating positional signals for spatial patterning in imaginal disc development is discussed.
This article has been cited by other articles:
|
|
 |
|
  F. Prince, T. Katsuyama, Y. Oshima, S. Plaza, D. Resendez-Perez, M. Berry, S. Kurata, and W. J. Gehring The YPWM motif links Antennapedia to the basal transcriptional machinery Development, May 1, 2008; 135(9): 1669 - 1679. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Hayward, T. Kalmar, and A. Martinez Arias Wnt/Notch signalling and information processing during development Development, February 1, 2008; 135(3): 411 - 424. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Chung, S. Kim, J. Yoon, P. N. Adler, and J. Yim The Balance Between the Novel Protein Target of Wingless and the Drosophila Rho-Associated Kinase Pathway Regulates Planar Cell Polarity in the Drosophila Wing Genetics, June 1, 2007; 176(2): 891 - 903. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. M. Goodman, S. Thombre, Z. Firtina, D. Gray, D. Betts, J. Roebuck, E. P. Spana, and E. M. Selva Sprinter: a novel transmembrane protein required for Wg secretion and signaling Development, December 15, 2006; 133(24): 4901 - 4911. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. S. Seto and H. J. Bellen Internalization is required for proper Wingless signaling in Drosophila melanogaster. J. Cell Biol., April 10, 2006; 173(1): 95 - 106. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. J. Krupp, L. E. Yaich, R. J. Wessells, and R. Bodmer Identification of Genetic Loci That Interact With cut During Drosophila Wing-Margin Development Genetics, August 1, 2005; 170(4): 1775 - 1795. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Kon, K. M. Cadigan, S. L. da Silva, and R. Nusse Developmental Roles of the Mi-2/NURD-Associated Protein p66 in Drosophila Genetics, April 1, 2005; 169(4): 2087 - 2100. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
X. Franch-Marro, O. Marchand, E. Piddini, S. Ricardo, C. Alexandre, and J.-P. Vincent Glypicans shunt the Wingless signal between local signalling and further transport Development, February 15, 2005; 132(4): 659 - 666. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Amoyel, Y.-C. Cheng, Y.-J. Jiang, and D. G. Wilkinson Wnt1 regulates neurogenesis and mediates lateral inhibition of boundary cell specification in the zebrafish hindbrain Development, February 15, 2005; 132(4): 775 - 785. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. A. Zeng and E. M. Verheyen Nemo is an inducible antagonist of Wingless signaling during Drosophila wing development Development, June 15, 2004; 131(12): 2911 - 2920. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Hirabayashi, Y. Itoh, H. Tabata, K. Nakajima, T. Akiyama, N. Masuyama, and Y. Gotoh The Wnt/{beta}-catenin pathway directs neuronal differentiation of cortical neural precursor cells Development, June 15, 2004; 131(12): 2791 - 2801. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Bajpai, K. Makhijani, P. R. Rao, and L. S. Shashidhara Drosophila Twins regulates Armadillo levels in response to Wg/Wnt signal Development, March 1, 2004; 131(5): 1007 - 1016. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. J. Giraldez and S. M. Cohen Wingless and Notch signaling provide cell survival cues and control cell proliferation during wing development Development, December 29, 2003; 130(26): 6533 - 6543. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Lei, A. Xu, V. M. Panin, and K. D. Irvine An O-fucose site in the ligand binding domain inhibits Notch activation Development, December 29, 2003; 130(26): 6411 - 6421. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. Schweizer, D. Nellen, and K. Basler Requirement for Pangolin/dTCF in Drosophila Wingless signaling PNAS, May 13, 2003; 100(10): 5846 - 5851. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. A. Dansereau, M. D. Lunke, A. Finkielsztein, M. A. Russell, and W. J. Brook hephaestus encodes a polypyrimidine tract binding protein that regulates Notch signalling during wing development in Drosophila melanogaster Development, March 14, 2003; 129(24): 5553 - 5566. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. A. Micchelli, I. The, E. Selva, V. Mogila, and N. Perrimon rasp, a putative transmembrane acyltransferase, is required for Hedgehog signaling Development, March 4, 2003; 129(4): 843 - 851. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. Heitzler, L. Vanolst, I. Biryukova, and P. Ramain Enhancer-promoter communication mediated by Chip during Pannier-driven proneural patterning is regulated by Osa Genes & Dev., March 1, 2003; 17(5): 591 - 596. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. J. Butler, T. L. Jacobsen, D. M. Cain, M. G. Jarman, M. Hubank, J. R. S. Whittle, R. Phillips, and A. Simcox Discovery of genes with highly restricted expression patterns in the Drosophila wing disc using DNA oligonucleotide microarrays Development, February 15, 2003; 130(4): 659 - 670. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. d. A. Rodriguez, J. Terriente, M. I. Galindo, J. P. Couso, and F. J. Diaz-Benjumea Different mechanisms initiate and maintain wingless expression in the Drosophila wing hinge Development, September 1, 2002; 129(17): 3995 - 4004. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
O. Gerlitz and K. Basler Wingful, an extracellular feedback inhibitor of Wingless Genes & Dev., May 1, 2002; 16(9): 1055 - 1059. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. D. Axelrod Unipolar membrane association of Dishevelled mediates Frizzled planar cell polarity signaling Genes & Dev., May 15, 2001; 15(10): 1182 - 1187. [Abstract] [Full Text]
|
|
|
|
|
|
R. Nolo, L. A. Abbott, and H. J. Bellen Drosophila Lyra Mutations Are Gain-of-Function Mutations of senseless Genetics, January 1, 2001; 157(1): 307 - 315. [Abstract] [Full Text]
|
|
|
|
|
|
S. Abdelilah-Seyfried, Y.-M. Chan, C. Zeng, N. J. Justice, S. Younger-Shepherd, L. E. Sharp, S. Barbel, S. A. Meadows, L. Y. Jan, and Y. N. Jan A Gain-of-Function Screen for Genes That Affect the Development of the Drosophila Adult External Sensory Organ Genetics, June 1, 2000; 155(2): 733 - 752. [Abstract] [Full Text]
|
|
|
|
|
|
C. Conley, R Silburn, M. Singer, A Ralston, D Rohwer-Nutter, D. Olson, W Gelbart, and S. Blair Crossveinless 2 contains cysteine-rich domains and is required for high levels of BMP-like activity during the formation of the cross veins in Drosophila Development, January 9, 2000; 127(18): 3947 - 3959. [Abstract] [PDF]
|
|
|
|
|
|
S. Day and P. Lawrence Measuring dimensions: the regulation of size and shape Development, January 7, 2000; 127(14): 2977 - 2987. [Abstract] [PDF]
|
|
|
|
|
|
R. D. del Corral, P. Aroca, J. L. Gómez-Skarmeta, F. Cavodeassi, and J. Modolell The Iroquois homeodomain proteins are required to specify body wall identity in Drosophila Genes & Dev., July 1, 1999; 13(13): 1754 - 1761. [Abstract] [Full Text]
|
|
|
|
|
|
C. Chen and G Struhl Wingless transduction by the Frizzled and Frizzled2 proteins of Drosophila Development, January 12, 1999; 126(23): 5441 - 5452. [Abstract] [PDF]
|
|
|
|
 |
|
 S Dennis, M Aikawa, W Szeto, P. d'Amore, and J Papkoff A secreted frizzled related protein, FrzA, selectively associates with Wnt-1 protein and regulates wnt-1 signaling J. Cell Sci., January 11, 1999; 112(21): 3815 - 3820. [Abstract] [PDF]
|
|
|
|
|
|
K Willert, C. Logan, A Arora, M Fish, and R Nusse A Drosophila Axin homolog, Daxin, inhibits Wnt signaling Development, January 9, 1999; 126(18): 4165 - 4173. [Abstract] [PDF]
|
|
|
|
|
|
M. Garcia-Garcia, P Ramain, P Simpson, and J Modolell Different contributions of pannier and wingless to the patterning of the dorsal mesothorax of Drosophila Development, January 8, 1999; 126(16): 3523 - 3532. [Abstract] [PDF]
|
|
|
|
|
|
G Morata and E Sanchez-Herrero Patterning mechanisms in the body trunk and the appendages of Drosophila Development, January 7, 1999; 126(13): 2823 - 2828. [Abstract] [PDF]
|
|
|
|
|
|
J. de Celis, R Barrio, and F. Kafatos Regulation of the spalt/spalt-related gene complex and its function during sensory organ development in the Drosophila thorax Development, January 6, 1999; 126(12): 2653 - 2662. [Abstract] [PDF]
|
|
|
|
|
|
P Simpson, R Woehl, and K Usui The development and evolution of bristle patterns in Diptera Development, January 4, 1999; 126(7): 1349 - 1364. [Abstract] [PDF]
|
|
|
|
|
|
M Sato, T Kojima, T Michiue, and K Saigo Bar homeobox genes are latitudinal prepattern genes in the developing Drosophila notum whose expression is regulated by the concerted functions of decapentaplegic and wingless Development, January 4, 1999; 126(7): 1457 - 1466. [Abstract] [PDF]
|
|
|
|
|
|
R Nagaraj, A. Pickup, R Howes, K Moses, M Freeman, and U Banerjee Role of the EGF receptor pathway in growth and patterning of the Drosophila wing through the regulation of vestigial Development, January 2, 1999; 126(5): 975 - 985. [Abstract] [PDF]
|
|
|
|
|
|
M. Milán, F. J. Diaz-Benjumea, and S. M. Cohen Beadex encodes an LMO protein that regulates Apterous LIM-homeodomain activity in Drosophila wing development: a model for LMO oncogene function Genes & Dev., September 15, 1998; 12(18): 2912 - 2920. [Abstract] [Full Text]
|
|
|
|
 |
|
 C. J. Neumann and S. M. Cohen Boundary Formation in Drosophila Wing: Notch Activity Attenuated by the POU Protein Nubbin Science, July 17, 1998; 281(5375): 409 - 413. [Abstract] [Full Text]
|
|
|
|
|
|
Y Tomoyasu, M Nakamura, and N Ueno Role of dpp signalling in prepattern formation of the dorsocentral mechanosensory organ in Drosophila melanogaster Development, January 11, 1998; 125(21): 4215 - 4224. [Abstract] [PDF]
|
|
|
|
|
|
G Campbell and A Tomlinson The roles of the homeobox genes aristaless and Distal-less in patterning the legs and wings of Drosophila Development, January 11, 1998; 125(22): 4483 - 4493. [Abstract] [PDF]
|
|
|
|
|
|
N Grillenzoni, J van Helden, C Dambly-Chaudiere, and A Ghysen The iroquois complex controls the somatotopy of Drosophila notum mechanosensory projections Development, January 9, 1998; 125(18): 3563 - 3569. [Abstract] [PDF]
|
|
|
|
|
|
J Zhang and R. Carthew Interactions between Wingless and DFz2 during Drosophila wing development Development, January 8, 1998; 125(16): 3075 - 3085. [Abstract] [PDF]
|
|
|
|
|
|
M. Go, D. Eastman, and S Artavanis-Tsakonas Cell proliferation control by Notch signaling in Drosophila development Development, January 6, 1998; 125(11): 2031 - 2040. [Abstract] [PDF]
|
|
|
|
|
|
Y. Cubadda, P. Heitzler, R. P. Ray, M. Bourouis, P. Ramain, W. Gelbart, P. Simpson, and M. Haenlin u-shaped encodes a zinc finger protein that regulates the proneural genes achaete and scute during the formation of bristles in Drosophila Genes & Dev., November 15, 1997; 11(22): 3083 - 3095. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. E. Treisman, A. Luk, G. M. Rubin, and U. Heberlein eyelid antagonizes wingless signaling during Drosophila development and has homology to the Bright family of DNA-binding proteins Genes & Dev., August 1, 1997; 11(15): 1949 - 1962. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A Majumdar, R Nagaraj, and U Banerjee strawberry notch encodes a conserved nuclear protein that functions downstream of Notch and regulates gene expression along the developing wing margin of Drosophila. Genes & Dev., May 15, 1997; 11(10): 1341 - 1353. [Abstract] [PDF]
|
|
|
|
|
|
J Heasman Patterning the Xenopus blastula Development, January 11, 1997; 124(21): 4179 - 4191. [Abstract] [PDF]
|
|
|
|
|
|
L Seugnet, P Simpson, and M Haenlin Transcriptional regulation of Notch and Delta: requirement for neuroblast segregation in Drosophila Development, January 5, 1997; 124(10): 2015 - 2025. [Abstract] [PDF]
|
|
|
|
|
|
C. Micchelli, E. Rulifson, and S. Blair The function and regulation of cut expression on the wing margin of Drosophila: Notch, Wingless and a dominant negative role for Delta and Serrate Development, January 4, 1997; 124(8): 1485 - 1495. [Abstract] [PDF]
|
|
|
|
|
|
C. Neumann and S. Cohen Long-range action of Wingless organizes the dorsal-ventral axis of the Drosophila wing Development, January 2, 1997; 124(4): 871 - 880. [Abstract] [PDF]
|
|
|
|
|
|
T Kadowaki, E Wilder, J Klingensmith, K Zachary, and N Perrimon The segment polarity gene porcupine encodes a putative multitransmembrane protein involved in Wingless processing. Genes & Dev., December 15, 1996; 10(24): 3116 - 3128. [Abstract] [PDF]
|
|
|
|
|
|
J L Gomez-Skarmeta and J Modolell araucan and caupolican provide a link between compartment subdivisions and patterning of sensory organs and veins in the Drosophila wing. Genes & Dev., November 15, 1996; 10(22): 2935 - 2945. [Abstract] [PDF]
|
|
|
|
|
|
D Doherty, G Feger, S Younger-Shepherd, L Y Jan, and Y N Jan Delta is a ventral to dorsal signal complementary to Serrate, another Notch ligand, in Drosophila wing formation. Genes & Dev., February 15, 1996; 10(4): 421 - 434. [Abstract] [PDF]
|
|
|
|
|
|
C. Neumann and S. Cohen A hierarchy of cross-regulation involving Notch, wingless, vestigial and cut organizes the dorsal/ventral axis of the Drosophila wing Development, January 11, 1996; 122(11): 3477 - 3485. [Abstract] [PDF]
|
|
|
|
|
|
K. Cadigan and R Nusse wingless signaling in the Drosophila eye and embryonic epidermis Development, January 9, 1996; 122(9): 2801 - 2812. [Abstract] [PDF]
|
|
|
|
|
|
C. Neumann and S. Cohen Distinct mitogenic and cell fate specification functions of wingless in different regions of the wing Development, January 6, 1996; 122(6): 1781 - 1789. [Abstract] [PDF]
|
|
|
|
|
|
J. de Celis, A Garcia-Bellido, and S. Bray Activation and function of Notch at the dorsal-ventral boundary of the wing imaginal disc Development, January 1, 1996; 122(1): 359 - 369. [Abstract] [PDF]
|
|
|
|
|
|
F. Diaz-Benjumea and S. Cohen Serrate signals through Notch to establish a Wingless-dependent organizer at the dorsal/ventral compartment boundary of the Drosophila wing Development, January 12, 1995; 121(12): 4215 - 4225. [Abstract] [PDF]
|
|
|
|
|
|
J. Treisman and G. Rubin wingless inhibits morphogenetic furrow movement in the Drosophila eye disc Development, January 11, 1995; 121(11): 3519 - 3527. [Abstract] [PDF]
|
|
|
|
|
|
J. de Celis, M Llimargas, and J Casanova Ventral veinless, the gene encoding the Cf1a transcription factor, links positional information and cell differentiation during embryonic and imaginal development in Drosophila melanogaster Development, January 10, 1995; 121(10): 3405 - 3416. [Abstract] [PDF]
|
|
|
|
|
|
E. Rulifson and S. Blair Notch regulates wingless expression and is not required for reception of the paracrine wingless signal during wing margin neurogenesis in Drosophila Development, January 9, 1995; 121(9): 2813 - 2824. [Abstract] [PDF]
|
|
|
|
|
|
M Ng, F. Diaz-Benjumea, and S. Cohen Nubbin encodes a POU-domain protein required for proximal-distal patterning in the Drosophila wing Development, January 2, 1995; 121(2): 589 - 599. [Abstract] [PDF]
|
|
|
|
|
|
S. Carroll, J Gates, D. Keys, S. Paddock, G. Panganiban, J. Selegue, and J. Williams Pattern formation and eyespot determination in butterfly wings Science, July 1, 1994; 265(5168): 109 - 114. [Abstract] [PDF]
|
|
|
|
|
|
L Bally-Cuif and M Wassef Ectopic induction and reorganization of Wnt-1 expression in quail/chick chimeras Development, January 12, 1994; 120(12): 3379 - 3394. [Abstract] [PDF]
|
|
|
|
|
|
